Dioctosoftez

Generic Name: docusate (DOK ue sate)

Brand Names: Calcium Stool Softener, Colace, Correctol Softgel Extra Gentle, D-S Caps, Diocto, Doc-Q-Lace, Docu, Docu Soft, Doculase, Docusoft S, DocuSol, DOK, DOS, DSS, Dulcolax Stool Softener, Enemeez Mini, Fleet Sof-Lax, Kao-Tin, Kaopectate Stool Softener, Kasof, Phillips Stool Softener, Silace, Sur-Q-Lax

What is Dioctosoftez (docusate)?

Docusate is a stool softener. It makes bowel movements softer and easier to pass.

Docusate is used to treat or prevent constipation, and to reduce pain or rectal damage caused by hard stools or by straining during bowel movements.

Docusate may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Dioctosoftez (docusate)?

You should not use docusate if you are allergic to it, or if you have a blockage in your intestines. Do not use docusate while you are sick with nausea, vomiting, or stomach pain. Do not take mineral oil while using docusate, unless your doctor tells you to.

Ask a doctor or pharmacist before using docusate if you are on a low-salt diet, if you are pregnant or breast-feeding, or if you have recently had a sudden change in your bowel habits lasting for longer than 2 weeks.

What should I discuss with my healthcare provider before using Dioctosoftez (docusate)?

You should not use docusate if you are allergic to it, or if you have a blockage in your intestines. Do not use docusate while you are sick with nausea, vomiting, or stomach pain. Do not take mineral oil while using docusate, unless your doctor tells you to.

Ask a doctor or pharmacist if it is safe for you to take docusate:

• 
  

  if you are on a low-salt diet; or

  
  


• 
  

  if you have recently had a sudden change in your bowel habits lasting for longer than 2 weeks.

  
  

It is not known whether docusate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether docusate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child younger than 2 years old without the advice of a doctor.

How should I use Dioctosoftez (docusate)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Take docusate tablets or capsules with a full glass of water. Drink plenty of liquids while you are taking docusate. Do not crush, chew, or break a docusate capsule. Swallow it whole.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Mix the liquid with 6 to 8 ounces of milk, fruit juice, or infant formula and drink the mixture right away.

Do not take docusate rectal enema by mouth. It is for use only in your rectum. Wash your hands before and after using docusate rectal enema.

Try to empty your bowel and bladder just before using the enema.

Twist off the applicator tip. Lie down on your left side with your knees bent, and gently insert the tip of the enema applicator into the rectum. Squeeze the tube to empty the entire contents into the rectum. Throw away the tube, even if there is still some medicine left in it.

After using docusate, you should have a bowel movement within 12 to 72 hours. Call your doctor if you have not had a bowel movement within 1 to 3 days.

Do not use docusate for longer than 7 days unless your doctor has told you to. Overuse of a stool softener can lead to serious medical problems. Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Since docusate is used as needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting or stomach pain.

What should I avoid while using Dioctosoftez (docusate)?

Avoid using laxatives or other stool softeners unless your doctor has told you to.

Avoid using the bathroom just after using docusate enema.

Dioctosoftez (docusate) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using docusate and call your doctor at once if you have a serious side effect such as:

• 
  

  rectal bleeding or irritation;

  
  


• 
  

  numbness or a rash around your rectum;

  
  


• 
  

  severe diarrhea or stomach cramps; or

  
  


• 
  

  continued constipation.

  
  

Less serious side effects may include:

• 
  

  mild diarrhea; or

  
  


• 
  

  mild nausea.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Dioctosoftez (docusate)?

There may be other drugs that can interact with docusate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Dioctosoftez resources

• Dioctosoftez Side Effects (in more detail)
• Dioctosoftez Use in Pregnancy & Breastfeeding
• Dioctosoftez Drug Interactions
• Dioctosoftez Support Group
• 0 Reviews for Dioctosoftez - Add your own review/rating

• Docusate Professional Patient Advice (Wolters Kluwer)


• Colace MedFacts Consumer Leaflet (Wolters Kluwer)


• Diocto Liquid MedFacts Consumer Leaflet (Wolters Kluwer)


• Docusate Salts Monograph (AHFS DI)


• Dostinex Monograph (AHFS DI)


• Enemeez Mini Enema MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Dioctosoftez with other medications

• Constipation

Where can I get more information?

• Your pharmacist can provide more information about docusate.

See also: Dioctosoftez side effects (in more detail)

Diphenhydramine/Phenylephrine

Pronunciation: DYE-fen-HYE-dra-meen/FEN-il-EF-rin
Generic Name: Diphenhydramine/Phenylephrine
Brand Name: Generic only. No brands available.

Diphenhydramine/Phenylephrine is used for:

Temporarily relieving symptoms of hay fever, allergies, or the common cold, including nasal congestion, runny nose, sneezing, itching of the nose and throat, and itchy/watery eyes. It may also be used for other conditions as determined by your doctor.

Diphenhydramine/Phenylephrine is an antihistamine and decongestant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The decongestant promotes sinus and nasal drainage, relieving congestion and pressure.

Do NOT use Diphenhydramine/Phenylephrine if:

• you are allergic to any ingredient in Diphenhydramine/Phenylephrine


• you are taking sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the past 14 days


• you have severe high blood pressure, severe heart blood vessel disease, a rapid heartbeat, or severe heart problems

Contact your doctor or health care provider right away if any of these apply to you.

Before using Diphenhydramine/Phenylephrine:

Some medical conditions may interact with Diphenhydramine/Phenylephrine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a fast, slow, or irregular heartbeat


• if you have a history of glaucoma; high blood pressure; diabetes; heart problems; ulcers; stroke; asthma; an overactive thyroid; seizures; a blockage of the stomach, bowel, or bladder; trouble breathing when you sleep; trouble sleeping; lung problems (eg, emphysema); the blood disease porphyria; an enlarged prostate or other prostate problems; adrenal gland problems; or blood vessel problems; or if you have difficulty urinating


• if you have a chronic cough or if your cough occurs with large amounts of mucus

Some MEDICINES MAY INTERACT with Diphenhydramine/Phenylephrine. Tell your health care provider if you are taking any other medicines, especially if any of the following apply to you:

• Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), indomethacin, furazolidone, MAOIs (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because side effects such as severe headache, high blood pressure, or high fever may occur


• Bromocriptine or sodium oxybate (GHB) because the risk of their side effects or toxic effects may be increased by Diphenhydramine/Phenylephrine


• Guanethidine, guanadrel, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Diphenhydramine/Phenylephrine.


• Digoxin or droxidopa because side effects such as irregular heartbeat or heart attack may occur


• Urinary alkalinizers (eg, sodium bicarbonate) because they may increase the risk of Diphenhydramine/Phenylephrine's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Diphenhydramine/Phenylephrine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Diphenhydramine/Phenylephrine:

Use Diphenhydramine/Phenylephrine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Diphenhydramine/Phenylephrine by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• If you miss a dose of Diphenhydramine/Phenylephrine and are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Diphenhydramine/Phenylephrine.

Important safety information:

• Diphenhydramine/Phenylephrine may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Diphenhydramine/Phenylephrine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not drink alcohol while you are using Diphenhydramine/Phenylephrine. Talk with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Diphenhydramine/Phenylephrine; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• Contact your health care provider if symptoms last for more than 7 days, get worse, or occur with fever, rash, or persistent headache.


• Diabetes patients - Diphenhydramine/Phenylephrine may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.


• Diphenhydramine/Phenylephrine contains phenylephrine and diphenhydramine. Before you begin taking any new prescription or nonprescription medicine, including medicine used on the skin, read the ingredients to see if it has phenylephrine or diphenhydramine in it too. If it does or if you are not sure, contact your doctor or pharmacist.


• Diphenhydramine/Phenylephrine may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Diphenhydramine/Phenylephrine for a few days before the tests.


• Do not take diet or appetite control medicines while you are taking Diphenhydramine/Phenylephrine without checking with your doctor.


• Do not use Diphenhydramine/Phenylephrine for a cough with a lot of mucous. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.


• Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.


• If you have trouble sleeping, ask your pharmacist or doctor about the best time of day to take Diphenhydramine/Phenylephrine.


• Use Diphenhydramine/Phenylephrine with caution in the ELDERLY; they may be more sensitive to its effects.


• Diphenhydramine/Phenylephrine is not recommended for use in NEWBORNS; safety and effectiveness have not been confirmed.


• Do not use Diphenhydramine/Phenylephrine in CHILDREN younger than 12 years old without checking with the child's doctor; safety and effectiveness in these children have not been confirmed.


• Caution is advised when using Diphenhydramine/Phenylephrine in CHILDREN; they may be more sensitive to its effects, especially excitability.


• PREGNANCY AND BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Diphenhydramine/Phenylephrine while you are pregnant. If you are or will be breast-feeding while you use Diphenhydramine/Phenylephrine, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Diphenhydramine/Phenylephrine:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability (especially in children); headache; loss of appetite; nausea; nervousness; restlessness; trouble sleeping; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; chest pain; decreased coordination; difficulty urinating; fast or irregular heartbeat; fever; hallucinations; seizure; severe dizziness or drowsiness; severe nervousness, anxiety, restlessness, or trouble sleeping; tremors; unusual weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Diphenhydramine/Phenylephrine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include bluish-colored skin; difficulty breathing; dilated pupils; fast or irregular heartbeat; fever; flushing; hallucinations; mental or mood changes; seizures; severe drowsiness or dizziness; severe excitability; severe nausea or vomiting; sweating; tremors.

Proper storage of Diphenhydramine/Phenylephrine:

Store Diphenhydramine/Phenylephrine at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Diphenhydramine/Phenylephrine out of the reach of children and away from pets.

General information:

• If you have any questions about Diphenhydramine/Phenylephrine, please talk with your doctor, pharmacist, or other health care provider.


• Diphenhydramine/Phenylephrine is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Diphenhydramine/Phenylephrine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Diphenhydramine/Phenylephrine resources

• Diphenhydramine/Phenylephrine Side Effects (in more detail)
• Diphenhydramine/Phenylephrine Use in Pregnancy & Breastfeeding
• Drug Images
• Diphenhydramine/Phenylephrine Drug Interactions
• Diphenhydramine/Phenylephrine Support Group
• 1 Review for Diphenhydramine/Phenylephrine - Add your own review/rating

Compare Diphenhydramine/Phenylephrine with other medications

• Cold Symptoms
• Hay Fever
• Sinusitis

Diphen Cough

Generic Name: diphenhydramine (DYE fen HYE dra meen)

Brand Names: Aler-Tab, Allergy, Allermax, Altaryl, Benadryl Allergy, Benadryl DF, Benadryl Dye Free Allergy, Benadryl Ultratab, Children's Allergy, Diphen Cough, Diphenhist, Dytuss, PediaCare Children's Allergy, Q-Dryl, Q-Dryl A/F, Siladryl, Siladryl Allergy, Silphen Cough, Simply Sleep, Sleep-ettes, Sleep-ettes D, Sominex Maximum Strength Caplet, Theraflu Thin Strips Multi Symptom, Triaminic Thin Strips Cough & Runny Nose, Unisom Sleepgels Maximum Strength, Valu-Dryl

What is Diphen Cough (diphenhydramine)?

Diphenhydramine is an antihistamine. Diphenhydramine blocks the effects of the naturally occurring chemical histamine in the body.

Diphenhydramine is used to treat sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold.

Diphenhydramine is also used to suppress coughs, to treat motion sickness, to induce sleep, and to treat mild forms of Parkinson's disease.

Diphenhydramine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Diphen Cough (diphenhydramine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking diphenhydramine.

What should I discuss with my healthcare provider before taking Diphen Cough (diphenhydramine)?

Do not take diphenhydramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

• 
  

  glaucoma or increased pressure in the eye;

  
  


• 
  

  a stomach ulcer;

  
  


• 
  

  an enlarged prostate, bladder problems or difficulty urinating;

  
  


• 
  

  an overactive thyroid (hyperthyroidism);

  
  


• 
  

  hypertension or any type of heart problems; or

  
  


• 
  

  asthma.

  
  

You may not be able to take diphenhydramine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Diphenhydramine is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not take diphenhydramine without first talking to your doctor if you are pregnant. Infants are especially sensitive to the effects of antihistamines, and side effects could occur in a breast-feeding baby. Do not take diphenhydramine without first talking to your doctor if you are nursing a baby. If you are over 60 years of age, you may be more likely to experience side effects from diphenhydramine. You may require a lower dose of this medication.

How should I take Diphen Cough (diphenhydramine)?

Take diphenhydramine exactly as directed on the package or as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Diphenhydramine can be taken with or without food.

For motion sickness, a dose is usually taken 30 minutes before motion, then with meals and at bedtime for the duration of exposure.

As a sleep aid, diphenhydramine should be taken approximately 30 minutes before bedtime.

To ensure that you get a correct dose, measure the liquid forms of diphenhydramine with a special dose-measuring spoon or cup, not with a regular tablespoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Never take more of this medication than is prescribed for you. The maximum amount of diphenhydramine that you should take in any 24-hour period is 300 mg.

Store diphenhydramine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a diphenhydramine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.

What should I avoid while taking Diphen Cough (diphenhydramine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking diphenhydramine.

Diphen Cough (diphenhydramine) side effects

Stop taking diphenhydramine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take diphenhydramine and talk to your doctor if you experience

• 
  

  sleepiness, fatigue, or dizziness;

  
  


• 
  

  headache;

  
  


• 
  

  dry mouth; or

  
  


• 
  

  difficulty urinating or an enlarged prostate.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Diphen Cough (diphenhydramine)?

Do not take diphenhydramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Talk to your pharmacist before taking other over-the-counter cough, cold, allergy, or insomnia medications. These products may contain medicines similar to diphenhydramine, which could lead to an antihistamine overdose.

Before taking this medication, tell your doctor if you are taking any of the following medicines:

• 
  

  anxiety or sleep medicines such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), temazepam (Restoril), or triazolam (Halcion);

  
  


• 
  

  medications for depression such as amitriptyline (Elavil), doxepin (Sinequan), nortriptyline (Pamelor), fluoxetine (Prozac), sertraline (Zoloft), or paroxetine (Paxil); or

  
  


• 
  

  any other medications that make you feel drowsy, sleepy, or relaxed.

  
  

Drugs other than those listed here may also interact with diphenhydramine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

More Diphen Cough resources

• Diphen Cough Side Effects (in more detail)
• Diphen Cough Use in Pregnancy & Breastfeeding
• Diphen Cough Drug Interactions
• Diphen Cough Support Group
• 0 Reviews for Diphen Cough - Add your own review/rating

• Banophen MedFacts Consumer Leaflet (Wolters Kluwer)


• Ben-Tann Suspension MedFacts Consumer Leaflet (Wolters Kluwer)


• Benadryl Consumer Overview


• Benadryl Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Benadryl Allergy Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• Children's Allergy Prescribing Information (FDA)


• Diphen Advanced Consumer (Micromedex) - Includes Dosage Information


• Diphenhydramine MedFacts Consumer Leaflet (Wolters Kluwer)


• Diphenhydramine Prescribing Information (FDA)


• Diphenhydramine Hydrochloride Monograph (AHFS DI)


• Diphenoxylate Hydrochloride Monograph (AHFS DI)


• Dytuss Elixir MedFacts Consumer Leaflet (Wolters Kluwer)


• Simply Sleep MedFacts Consumer Leaflet (Wolters Kluwer)


• Sominex MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Diphen Cough with other medications

• Cough

Where can I get more information?

• Your pharmacist can provide more information about diphenhydramine.

See also: Diphen Cough side effects (in more detail)

Docu

Generic Name: docusate (DOK ue sate)

Brand Names: Calcium Stool Softener, Colace, Correctol Softgel Extra Gentle, D-S Caps, Diocto, Doc-Q-Lace, Docu, Docu Soft, Doculase, Docusoft S, DocuSol, DOK, DOS, DSS, Dulcolax Stool Softener, Enemeez Mini, Fleet Sof-Lax, Kao-Tin, Kaopectate Stool Softener, Kasof, Phillips Stool Softener, Silace, Sur-Q-Lax

What is Docu (docusate)?

Docusate is a stool softener. It makes bowel movements softer and easier to pass.

Docusate is used to treat or prevent constipation, and to reduce pain or rectal damage caused by hard stools or by straining during bowel movements.

Docusate may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Docu (docusate)?

You should not use docusate if you are allergic to it, or if you have a blockage in your intestines. Do not use docusate while you are sick with nausea, vomiting, or stomach pain. Do not take mineral oil while using docusate, unless your doctor tells you to.

Ask a doctor or pharmacist before using docusate if you are on a low-salt diet, if you are pregnant or breast-feeding, or if you have recently had a sudden change in your bowel habits lasting for longer than 2 weeks.

What should I discuss with my healthcare provider before using Docu (docusate)?

You should not use docusate if you are allergic to it, or if you have a blockage in your intestines. Do not use docusate while you are sick with nausea, vomiting, or stomach pain. Do not take mineral oil while using docusate, unless your doctor tells you to.

Ask a doctor or pharmacist if it is safe for you to take docusate:

• 
  

  if you are on a low-salt diet; or

  
  


• 
  

  if you have recently had a sudden change in your bowel habits lasting for longer than 2 weeks.

  
  

It is not known whether docusate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether docusate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child younger than 2 years old without the advice of a doctor.

How should I use Docu (docusate)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Take docusate tablets or capsules with a full glass of water. Drink plenty of liquids while you are taking docusate. Do not crush, chew, or break a docusate capsule. Swallow it whole.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Mix the liquid with 6 to 8 ounces of milk, fruit juice, or infant formula and drink the mixture right away.

Do not take docusate rectal enema by mouth. It is for use only in your rectum. Wash your hands before and after using docusate rectal enema.

Try to empty your bowel and bladder just before using the enema.

Twist off the applicator tip. Lie down on your left side with your knees bent, and gently insert the tip of the enema applicator into the rectum. Squeeze the tube to empty the entire contents into the rectum. Throw away the tube, even if there is still some medicine left in it.

After using docusate, you should have a bowel movement within 12 to 72 hours. Call your doctor if you have not had a bowel movement within 1 to 3 days.

Do not use docusate for longer than 7 days unless your doctor has told you to. Overuse of a stool softener can lead to serious medical problems. Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Since docusate is used as needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting or stomach pain.

What should I avoid while using Docu (docusate)?

Avoid using laxatives or other stool softeners unless your doctor has told you to.

Avoid using the bathroom just after using docusate enema.

Docu (docusate) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using docusate and call your doctor at once if you have a serious side effect such as:

• 
  

  rectal bleeding or irritation;

  
  


• 
  

  numbness or a rash around your rectum;

  
  


• 
  

  severe diarrhea or stomach cramps; or

  
  


• 
  

  continued constipation.

  
  

Less serious side effects may include:

• 
  

  mild diarrhea; or

  
  


• 
  

  mild nausea.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Docu (docusate)?

There may be other drugs that can interact with docusate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Docu resources

• Docu Side Effects (in more detail)
• Docu Use in Pregnancy & Breastfeeding
• Docu Drug Interactions
• Docu Support Group
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• Your pharmacist can provide more information about docusate.

See also: Docu side effects (in more detail)

Dinoprost tromethamine Injection

Available Dosage Forms:

• Injectable


• Solution

Pharmacologic Class: Dinoprost

Uses For dinoprost tromethamine

Dinoprost is used to cause abortion during the second trimester of pregnancy. It may also be used for other purposes as determined by your doctor.

Dinoprost is to be administered only by or under the immediate care of your doctor.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not specifically included in product labeling, dinoprost is used in certain patients for the following medical procedures:

• Angiography (x-ray pictures of the blood vessels)


• Inducing labor

Before Using dinoprost tromethamine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For dinoprost tromethamine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to dinoprost tromethamine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of dinoprost tromethamine. Make sure you tell your doctor if you have any other medical problems, especially:

• Anemia (history of)—In some patients, abortion with dinoprost may result in loss of blood that may require a transfusion

• Asthma (or history of) or


• Lung disease—Dinoprost may cause narrowing of the blood vessels in the lungs or narrowing of the lung passages

• Type 2 diabetes mellitus (history of)

• Epilepsy (or history of)—Rarely, dinoprost has been reported to cause seizures in patients who have epilepsy

• Fibroid tumors of the uterus or


• Uterus surgery (history of)—There is an increased risk of rupture of the uterus

• Glaucoma—Rarely the pressure within the eye has increased and constriction of the pupils has occurred during the use of dinoprost

• Heart or blood vessel disease (or history of) or


• High blood pressure (history of) or


• Low blood pressure (history of)—Dinoprost may cause changes in heart function or blood pressure changes

• Jaundice (history of)

• Kidney disease (or history of)

• Liver disease (or history of)—The body may not get dinoprost out of the bloodstream at the usual rate, which may make the medicine work longer or cause toxic effects

Proper Use of dinoprost tromethamine

Dosing

The dose of dinoprost tromethamine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of dinoprost tromethamine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For injection dosage form:
  
  • For aborting a pregnancy:
    
    • Adults—Your doctor will slowly inject 40 milligrams (mg) into the amniotic sac (bag that surrounds the fetus). If needed, your doctor may give you another dose in twenty–four hours to complete the abortion.
    
    
  
  
  • For inducing labor:
    
    • Adults—Your doctor will slowly inject 1 to 4 mg a day into a vein.
    
    
  
  

dinoprost tromethamine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common or rare

• Chest pain


• coughing (sudden)


• cramping of the uterus (continuing and severe)


• fast heartbeat


• hives


• numbness in legs or other body parts


• pale, cool, or blotchy skin on arms or legs


• pressing or painful feeling in chest


• redness and itching of skin


• shortness of breath


• slow or irregular heartbeat


• swelling of eyelids, face, or inside of nose


• tightness in chest


• trouble in breathing


• weak or absent pulse in arms or legs


• wheezing

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare

• Abdominal or stomach pain (severe or continuing)


• blood in urine


• constipation


• decreased frequency of urination


• difficult or painful urination


• double vision or burning eyes


• pain in legs, back, or shoulder


• tender or mildly bloated abdomen

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Diarrhea


• nausea


• stomach cramps or pain


• vomiting

Less common

• Anxiety


• breast fullness or tenderness


• burning feeling in breasts


• chills or shivering


• cough (continuing)


• dizziness


• drowsiness


• fever (temporary)


• flushing or redness of face


• headache


• hiccups


• increased sweating


• inflammation and pain at place of injection


• unusual thirst

After the procedure has been completed, this procedure may still produce some side effects that need medical attention. Check with your doctor if you notice any of the following side effects:

• Chills or shivering (continuing)


• fever (continuing)


• foul-smelling vaginal discharge


• pain in lower abdomen


• unusual increase in uterus bleeding

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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